Take the diagnosis and management of soy-allergic patients to a whole new level

Why is soy allergy complicated to identify?

• IgE-mediated allergy to soy might be the result of primary sensitization, but could also result from cross-reactivity to birch-related tree pollen and a variety of legumes.
   
• IgE positivity to soy may be the result of different cross-reactivities, some without clinical reactions to soy.
   
• For patients sensitized to birch pollen with a suspicion of soy allergy, it is recommended to extend the testing with Gly m 4, which can be underrepresented in available tests based on extracts.
   
• Without components, it can be difficult to identify if your patient’s symptoms are actually due to soy.

Better identification of the soy-allergic patient...

• The presence of specific IgE to the storage proteins Gly m 5 and Gly m 6 indicates real soy allergy and risk of severe reactions.
   
• Sensitization to Gly m 4, a PR-10 protein, is common in patients allergic to birch-related tree pollen and indicates risk of reactions to soy. The reactions are often local, but might also be systemic.

...results in improved patient management

• Evaluate your patient’s risk of severe reactions to soy.
   
• Ensure relevant dietary advice and avoid unnecessary elimination.
   
• Define the optimal treatment for your patients.
   
• Proper diagnosis of patients with suspected soy allergy improves quality of life.